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mannose receptor c type 1  (MedChemExpress)


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    MedChemExpress mannose receptor c type 1
    Mannose Receptor C Type 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mannose receptor c type 1/product/MedChemExpress
    Average 92 stars, based on 2 article reviews
    mannose receptor c type 1 - by Bioz Stars, 2026-03
    92/100 stars

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    CVF treatment promotes M2-like polarization in ischemic muscle tissue. The scatter plot displays ( a ) the total number of macrophages (CD68 + ) per square millimeter (mm 2 ) and the percentage of ( b ) M1-like polarized macrophages (CD68 + <t>/MRC1</t> − ) and ( c ) M2-like polarized macrophages (CD68 + /MRC1 + ) in ischemic gastrocnemius muscle tissue at 7 days after femoral artery ligation (aFAL). Data are shown as means ± SEM, with n = 5 per group. ** p ≤ 0.01 and **** p ≤ 0.0001 (control vs. CVF) determined by unpaired Student’s t -tests. ( d ) Representative immunofluorescence images of analyzed ischemic gastrocnemius muscles from control (upper image) and CVF-treated mice (lower image) at 7 days aFAL. In single-channel pictures (small images on the right) and merged pictures (large images on the left), macrophages were labeled with CD68 antibody (green) and M2-like polarized macrophages were labeled with MRC1 antibody (red). Nuclei were labeled in merged images with DAPI (blue). Scale bars: 50 µm.
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    Image Search Results


    The mechanisms underlying occurrence of ferroptosis. (A) A schematic illustration of GSH-triggered and PTT-enhanced ferroptosis. (B) GSH contents normalized to the total protein concentration in MCF-7/ADR cells after different treatments ( n = 5). (C) Cellular protein expression of GPX-4 in MCF-7/ADR cells after treatments with I@P and I@P-ss-FRT (50 μg Fe/mL) with or without 808 nm laser exposure (1.25 W/cm 2 , 5 min) and (D) the relative level of GPX-4/β-actin ( n = 3). (E) CLSM images of MCF-7/ADR cells after incubation with I@P and I@P-ss-FRT showing intracellular Fe 2+ ions levels using fluorescent probe FerroOrange and (F) the quantification of fluorescence intensity inside cells; Scale bar = 50 μm ( n = 3). (G) CLSM images, (H) mean fluorescent intensity of the cells determined from the CLSM images, and (I) FCM analysis of ROS production in MCF-7/ADR cells after different treatments; Scale bar = 50 μm ( n = 3).

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    Article Title: Hyperthermia/glutathione-triggered ferritin nanoparticles amplify the ferroptosis for synergistic tumor therapy

    doi: 10.1016/j.mtbio.2024.101085

    Figure Lengend Snippet: The mechanisms underlying occurrence of ferroptosis. (A) A schematic illustration of GSH-triggered and PTT-enhanced ferroptosis. (B) GSH contents normalized to the total protein concentration in MCF-7/ADR cells after different treatments ( n = 5). (C) Cellular protein expression of GPX-4 in MCF-7/ADR cells after treatments with I@P and I@P-ss-FRT (50 μg Fe/mL) with or without 808 nm laser exposure (1.25 W/cm 2 , 5 min) and (D) the relative level of GPX-4/β-actin ( n = 3). (E) CLSM images of MCF-7/ADR cells after incubation with I@P and I@P-ss-FRT showing intracellular Fe 2+ ions levels using fluorescent probe FerroOrange and (F) the quantification of fluorescence intensity inside cells; Scale bar = 50 μm ( n = 3). (G) CLSM images, (H) mean fluorescent intensity of the cells determined from the CLSM images, and (I) FCM analysis of ROS production in MCF-7/ADR cells after different treatments; Scale bar = 50 μm ( n = 3).

    Article Snippet: Cell lysis buffer, phenylmethanesulfonylfluoride (PMSF), SDS-PAGE sample loading buffer, nonfat powdered milk, HRP-labeled goat anti-mouse IgG (H + L), HRP-labeled goat anti-rabbit IgG (H + L), BeyoECL Plus, BCA protein assay kit, Calcein/PI cell viability/cytotoxicity assay kit, reactive oxygen species (ROS) assay kit, mannose receptor C-type 1 (MRC1) rabbit polyclonal antibody and β-actin mouse monoclonal antibody were bought from Beyotime Biotechnology Co., Ltd (Shanghai, China).

    Techniques: Protein Concentration, Expressing, Incubation, Fluorescence

    The Up-Regulated and Down-Regulated Top 5 Proteins Between the Two Groups

    Journal: Journal of Inflammation Research

    Article Title: Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology

    doi: 10.2147/JIR.S444280

    Figure Lengend Snippet: The Up-Regulated and Down-Regulated Top 5 Proteins Between the Two Groups

    Article Snippet: Mannose receptor C-type 1 (MRC1) kits (Cat: CSB-E09961h), cadherin 13 (CDH13) kits (Cat: CSB-E13817h), cluster of differentiation 5 antigen-like (CD5L) kits (Cat: CSB-E13423h), matrix metalloproteinase-2 (MMP2) kits (Cat: CSB-E04675h), plasma protease C1 inhibitor (SERPING1) kits (Cat: CSB-EL021086HU), insulin-like growth factor-binding protein 5 (IGFBP5) kits (Cat: CSB-EL010901HU), tripartite motif-containing protein 28 (TRIM28) kits (Cat: CSB-EL024502HU), and fatty acid-binding protein 5 (FABP5) kits (Cat: CSB-EL007946HU) were purchased from Cusabio (Wuhan, China).

    Techniques: Clinical Proteomics

    Validation of the top 5 up and down-regulated proteins in an independent validation cohort. ( A – E ) comparison of serum MRC1, CDH13, LTA4H, CD5L and MMP2 concentrations between the eCRSwNP and neCRSwNP groups. ( F – J ) comparison of serum SERPING1, IGFBP5, TRIM28, CHL1 and FABP5 levels between the eCRSwNP and neCRSwNP groups. *P<0.05; **P<0.01; ***P<0.001.

    Journal: Journal of Inflammation Research

    Article Title: Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology

    doi: 10.2147/JIR.S444280

    Figure Lengend Snippet: Validation of the top 5 up and down-regulated proteins in an independent validation cohort. ( A – E ) comparison of serum MRC1, CDH13, LTA4H, CD5L and MMP2 concentrations between the eCRSwNP and neCRSwNP groups. ( F – J ) comparison of serum SERPING1, IGFBP5, TRIM28, CHL1 and FABP5 levels between the eCRSwNP and neCRSwNP groups. *P<0.05; **P<0.01; ***P<0.001.

    Article Snippet: Mannose receptor C-type 1 (MRC1) kits (Cat: CSB-E09961h), cadherin 13 (CDH13) kits (Cat: CSB-E13817h), cluster of differentiation 5 antigen-like (CD5L) kits (Cat: CSB-E13423h), matrix metalloproteinase-2 (MMP2) kits (Cat: CSB-E04675h), plasma protease C1 inhibitor (SERPING1) kits (Cat: CSB-EL021086HU), insulin-like growth factor-binding protein 5 (IGFBP5) kits (Cat: CSB-EL010901HU), tripartite motif-containing protein 28 (TRIM28) kits (Cat: CSB-EL024502HU), and fatty acid-binding protein 5 (FABP5) kits (Cat: CSB-EL007946HU) were purchased from Cusabio (Wuhan, China).

    Techniques: Biomarker Discovery, Comparison

    ROC curves evaluating the discriminative abilities of candidate proteins for eCRSwNP. ( A ) MRC1, ( B ) CDH13, ( C ) MMP2, ( D ) TRIM28.

    Journal: Journal of Inflammation Research

    Article Title: Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology

    doi: 10.2147/JIR.S444280

    Figure Lengend Snippet: ROC curves evaluating the discriminative abilities of candidate proteins for eCRSwNP. ( A ) MRC1, ( B ) CDH13, ( C ) MMP2, ( D ) TRIM28.

    Article Snippet: Mannose receptor C-type 1 (MRC1) kits (Cat: CSB-E09961h), cadherin 13 (CDH13) kits (Cat: CSB-E13817h), cluster of differentiation 5 antigen-like (CD5L) kits (Cat: CSB-E13423h), matrix metalloproteinase-2 (MMP2) kits (Cat: CSB-E04675h), plasma protease C1 inhibitor (SERPING1) kits (Cat: CSB-EL021086HU), insulin-like growth factor-binding protein 5 (IGFBP5) kits (Cat: CSB-EL010901HU), tripartite motif-containing protein 28 (TRIM28) kits (Cat: CSB-EL024502HU), and fatty acid-binding protein 5 (FABP5) kits (Cat: CSB-EL007946HU) were purchased from Cusabio (Wuhan, China).

    Techniques:

    ROC Curves of Serum Proteins in Predicting eCRSwNP

    Journal: Journal of Inflammation Research

    Article Title: Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology

    doi: 10.2147/JIR.S444280

    Figure Lengend Snippet: ROC Curves of Serum Proteins in Predicting eCRSwNP

    Article Snippet: Mannose receptor C-type 1 (MRC1) kits (Cat: CSB-E09961h), cadherin 13 (CDH13) kits (Cat: CSB-E13817h), cluster of differentiation 5 antigen-like (CD5L) kits (Cat: CSB-E13423h), matrix metalloproteinase-2 (MMP2) kits (Cat: CSB-E04675h), plasma protease C1 inhibitor (SERPING1) kits (Cat: CSB-EL021086HU), insulin-like growth factor-binding protein 5 (IGFBP5) kits (Cat: CSB-EL010901HU), tripartite motif-containing protein 28 (TRIM28) kits (Cat: CSB-EL024502HU), and fatty acid-binding protein 5 (FABP5) kits (Cat: CSB-EL007946HU) were purchased from Cusabio (Wuhan, China).

    Techniques:

    Multiplex immunofluorescence staining exploring the co-expressions of MRC1 ( A ), MMP2 ( B ), and eosinophil markers. Cells with evident co-expression are indicated by white arrows.

    Journal: Journal of Inflammation Research

    Article Title: Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology

    doi: 10.2147/JIR.S444280

    Figure Lengend Snippet: Multiplex immunofluorescence staining exploring the co-expressions of MRC1 ( A ), MMP2 ( B ), and eosinophil markers. Cells with evident co-expression are indicated by white arrows.

    Article Snippet: Mannose receptor C-type 1 (MRC1) kits (Cat: CSB-E09961h), cadherin 13 (CDH13) kits (Cat: CSB-E13817h), cluster of differentiation 5 antigen-like (CD5L) kits (Cat: CSB-E13423h), matrix metalloproteinase-2 (MMP2) kits (Cat: CSB-E04675h), plasma protease C1 inhibitor (SERPING1) kits (Cat: CSB-EL021086HU), insulin-like growth factor-binding protein 5 (IGFBP5) kits (Cat: CSB-EL010901HU), tripartite motif-containing protein 28 (TRIM28) kits (Cat: CSB-EL024502HU), and fatty acid-binding protein 5 (FABP5) kits (Cat: CSB-EL007946HU) were purchased from Cusabio (Wuhan, China).

    Techniques: Multiplex Assay, Immunofluorescence, Staining, Expressing

    CVF treatment promotes M2-like polarization in ischemic muscle tissue. The scatter plot displays ( a ) the total number of macrophages (CD68 + ) per square millimeter (mm 2 ) and the percentage of ( b ) M1-like polarized macrophages (CD68 + /MRC1 − ) and ( c ) M2-like polarized macrophages (CD68 + /MRC1 + ) in ischemic gastrocnemius muscle tissue at 7 days after femoral artery ligation (aFAL). Data are shown as means ± SEM, with n = 5 per group. ** p ≤ 0.01 and **** p ≤ 0.0001 (control vs. CVF) determined by unpaired Student’s t -tests. ( d ) Representative immunofluorescence images of analyzed ischemic gastrocnemius muscles from control (upper image) and CVF-treated mice (lower image) at 7 days aFAL. In single-channel pictures (small images on the right) and merged pictures (large images on the left), macrophages were labeled with CD68 antibody (green) and M2-like polarized macrophages were labeled with MRC1 antibody (red). Nuclei were labeled in merged images with DAPI (blue). Scale bars: 50 µm.

    Journal: Biomedicines

    Article Title: Treatment with Cobra Venom Factor Decreases Ischemic Tissue Damage in Mice

    doi: 10.3390/biomedicines12020309

    Figure Lengend Snippet: CVF treatment promotes M2-like polarization in ischemic muscle tissue. The scatter plot displays ( a ) the total number of macrophages (CD68 + ) per square millimeter (mm 2 ) and the percentage of ( b ) M1-like polarized macrophages (CD68 + /MRC1 − ) and ( c ) M2-like polarized macrophages (CD68 + /MRC1 + ) in ischemic gastrocnemius muscle tissue at 7 days after femoral artery ligation (aFAL). Data are shown as means ± SEM, with n = 5 per group. ** p ≤ 0.01 and **** p ≤ 0.0001 (control vs. CVF) determined by unpaired Student’s t -tests. ( d ) Representative immunofluorescence images of analyzed ischemic gastrocnemius muscles from control (upper image) and CVF-treated mice (lower image) at 7 days aFAL. In single-channel pictures (small images on the right) and merged pictures (large images on the left), macrophages were labeled with CD68 antibody (green) and M2-like polarized macrophages were labeled with MRC1 antibody (red). Nuclei were labeled in merged images with DAPI (blue). Scale bars: 50 µm.

    Article Snippet: Additionally, anti-CD45 − Alexa Fluor ® 488 antibody (1:100, Thermo Fisher, 11-0451-85) was used to label leukocytes, while anti-CD68-Alexa Fluor ® 488 antibody (1:200, Abcam, ab201844) and anti-mannose receptor C type 1 (anti-MRC1) antibody (1:200, Abcam, ab64693) were used to label macrophages and evaluate macrophage polarization.

    Techniques: Ligation, Immunofluorescence, Muscles, Labeling